Early Graft Dysfunction After Lung Transplantation
نویسندگان
چکیده
منابع مشابه
Primary Graft Dysfunction After Lung Transplantation.
Primary graft dysfunction is a form of acute injury after lung transplantation that is associated with significant short- and long-term morbidity and mortality. Multiple mechanisms contribute to the pathogenesis of primary graft dysfunction, including ischemia reperfusion injury, epithelial cell death, endothelial cell dysfunction, innate immune activation, oxidative stress, and release of infl...
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According to the International Society for Heart and Lung Transplantation (ISHLT) Registry, graft failure accounted for 24.7% of deaths within 30 days of transplantation among adult lung recipients between 1992 and 2012 [1]. Although important details distinguishing different causes of early graft failure may be missing from the Registry data, it is likely that primary graft dysfunction (PGD) i...
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in patients with end-stage lung diseases where other effective treatments are lacking [1]. However, the procedure is not without risks and side-effects. One of the most important causes of morbidity and mortality in these patients is infection [1, 2]. Recently, there has been an increase in the incidence of emerging infections, with the majority of mycobacterial infections due to Mycobacterium ...
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Lung transplantation is the treatment of choice for end-stage pulmonary diseases. A limited donor supply has resulted in 4,000 patients on the waiting list. Currently, 10-20% of donor organs offered for transplantation are deemed suitable under the selection criteria, of which 15-25% fail due to primary graft dysfunction (PGD). This has spawned efforts to re-examine the current selection criter...
متن کاملUPDATE IN INTENSIVE CARE: TRANSPLANTS Primary graft dysfunction after lung transplantation
Lung transplantation is a therapeutic option for pulmonary diseases in which the other treatment options have failed or in cases of rapid disease progression. However, trans-plantation is not free from complications, and primary graft dysfunction is one of them. Primary graft dysfunction is a form of acute lung injury. It characteristically develops during the immediate postoperative period, be...
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ژورنال
عنوان ژورنال: Current Pulmonology Reports
سال: 2018
ISSN: 2199-2428
DOI: 10.1007/s13665-018-0213-4